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1

ICH Topic: The draft ICH S7B step 2: Note for guidance on safety pharmacology studies for human pharmaceuticals

ICH Expert Working Group Topic Leaders:, Gerd Bode, Klaus Olejniczak

Journal:

Fundamental & Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 180 KB

english, 2002

2

Value-driven project and portfolio management in the pharmaceutical industry: Drug discovery versus drug development – Commonalities and differences in portfolio management practice

Bode-Greuel, Kerstin M, Nickisch, Klaus J

Journal:

Journal of Commercial Biotechnology

Year:

2008

Language:

english

File:

PDF, 205 KB

english, 2008

3

Carriage of ESBL-producing Gram-negative bacteria by flies captured in a hospital and its suburban surroundings in Ethiopia

Tufa, Tafese Beyene, Fuchs, Andre, Wienemann, Tobias, Eggers, Yannik, Abdissa, Sileshi, Schneider, Marlen, Jensen, BjÃ¶rn-Erik Ole, Bode, Johannes G., Pfeffer, Klaus, HÃ¤ussinger, Dieter, Mackenzie, C

Journal:

Antimicrobial Resistance and Infection Control

Year:

2020

File:

PDF, 882 KB

2020

4

Famciclovir treatment of hepatitis B virus recurrence after liver transplantation: A pilot study

Martin Krüger, Hans Ludger Tillmann, Christian Trautwein, Ulrike Bode, Karl Oldhafer, Hansjörg Maschek, Klaus H. W. Böker, Christoph E. Broelsch, Rudolf Pichlmayr, Michael P. Manns

Journal:

Liver Transplantation

Year:

1996

Language:

english

File:

PDF, 831 KB

english, 1996

5

ICH Topic: Note for guidance on safety pharmacology studies for human pharmaceuticals

Klaus Olejniczak, Gerd Bode

Journal:

Fundamental & Clinical Pharmacology

Year:

2002

Language:

english

File:

PDF, 42 KB

english, 2002

6

10.1038/23468

Kaupp, U. Benjamin, Körschen, Heinz G., Beyermann, Michael, Müller, Frank, Heck, Martin, Vantler, Marius, Koch, Karl-Wilhelm, Kellner, Roland, Wolfrum, Uwe, Bode, Christian, Hofmann, Klaus Peter

Journal:

Year:

1999

Language:

english

File:

PDF, 311 KB

english, 1999

7

Complete genome sequence of the myxobacterium Sorangium cellulosum

Schneiker, Susanne, Perlova, Olena, Kaiser, Olaf, Gerth, Klaus, Alici, Aysel, Altmeyer, Matthias O, Bartels, Daniela, Bekel, Thomas, Beyer, Stefan, Bode, Edna

Journal:

Nature Biotechnology

Year:

2007

Language:

english

File:

PDF, 658 KB

english, 2007

8

Outcome of acute respiratory distress syndrome requiring extracorporeal membrane oxygenation in Covidâ19 or influenza â a singleâcenter registry study

JÃ¤ckel, Markus, Rilinger, Jonathan, Lang, Corinna Nadine, Zotzmann, Viviane, Kaier, Klaus, Stachon, Peter, Marc Biever, Paul, Wengenmayer, Tobias, Duerschmied, Daniel, Bode, Christoph, Leander Stauda

Journal:

Artificial Organs

Year:

2020

File:

PDF, 9.63 MB

2020

9

Multicenter dose-finding trial for thrombolysis with urokinase preactivated pro-urokinase (TCL 598) in acute myocardial infarction

Dietrich C. Gulba, Christoph Bode, Semi Sen, Jürgen Topp, Klaus Fischer, Helmut Wolf, Hartmut Hecker

Journal:

Catheterization and Cardiovascular Interventions

Year:

1992

Language:

english

File:

PDF, 680 KB

english, 1992

10

Strukturwandel in der Ingenieurtechnik der chemischen Industrie – Wege zum Partner und Unternehmer

Dipl.-Ing. Diethard Francke, Dr.-Ing. Klaus P. Ochel, Ing. Walter Berger, Dr.-Ing. Ernst Sommer, Dr.-Ing. Henning Bode

Journal:

Chemie Ingenieur Technik

Year:

1994

Language:

german

File:

PDF, 794 KB

german, 1994

11

Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice

Sandra Goebbels, Ingo Bormuth, Ulli Bode, Ola Hermanson, Markus H. Schwab, Klaus-Armin Nave

Journal:

Year:

2006

Language:

english

File:

PDF, 1.64 MB

english, 2006

12

Cre/loxP-mediated inactivation of the bHLH transcription factor gene NeuroD/BETA2

Sandra Goebbels, Ulli Bode, Alexander Pieper, Ursula Funfschilling, Markus H. Schwab, Klaus-Armin Nave

Journal:

Year:

2005

Language:

english

File:

PDF, 529 KB

english, 2005

13

Prognostic factors for the malignant triton tumor of the head and neck

Andrej Terzic, Beata Bode, Klaus W. Gratz, Sandro J. Stoeckli

Journal:

Year:

2009

Language:

english

File:

PDF, 169 KB

english, 2009

14

(+)-Cyanidanol-3 in the Treatment of Acute Viral Hepatitis: A Randomized Controlled Trial

Hans Schomerus, Karl H. Wiedmann, Wolfgang Dölle, Herrmann Peerenboom, Georg Strohmeyer, Klaus Balzer, Harald Goebell, Hans K. Dürr, Christian Bode, André L. Blum, Gert Frösner, Wolfram Gerlich, Peter

Journal:

Year:

1984

Language:

english

File:

PDF, 461 KB

english, 1984

15

Über die Oxydationsprodukte von Thiocarbonsäureamiden, VII. Oxydationsreaktionen an Thioamiden der Oxalsäure

Wolfgang Walter, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1962

Language:

german

File:

PDF, 581 KB

german, 1962

16

Über die Oxydationsprodukte von Thiocarbonsäureamiden, IX Oxydationsreaktionen an Thionurethanen und Dithiourethanen

Wolfgang Walter, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1965

Language:

german

File:

PDF, 908 KB

german, 1965

17

Über die Oxydationsprodukte von Thiocarbonsäureamiden, X. Oxydationsreaktionen an Thiocarbamidsäure-O-estern und Dithiocarbamidsäureestern

Wolfgang Walter, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1966

Language:

german

File:

PDF, 546 KB

german, 1966

18

Über die Oxydationsprodukte von Thiocarbonsäureamiden, XVI. Oxydationsreaktionen an Thiocarbonsäureamiden mit elektronenanziehenden Substituenten am C-Atom

Wolfgang Walter, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1966

Language:

german

File:

PDF, 756 KB

german, 1966

19

Über die Oxydationsprodukte von Thiocarbonsäureamiden, XV. Oxydation von Thiocarbamidsäure-O-arylestern zu ortho-substituierten Aryloxy-iminomethansulfensäuren

Wolfgang Walter, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1966

Language:

german

File:

PDF, 416 KB

german, 1966

20

Übergänge aus der Benzoxazol- in die Benzoxazin-Reihe und umgekehrt, II1) Benzoxazol-2-carbonsäure-Derivate aus 2.3-Dioxo-1.4-benzoxazinen

Karlfried Dickoré, Klaus Sasse, Klaus-Dieter Bode

Journal:

European Journal of Organic Chemistry

Year:

1970

File:

PDF, 821 KB

1970

21

Enantioselective quantification of omeprazole and its main metabolites in human serum by chiral HPLC–atmospheric pressure photoionization tandem mass spectrometry

Jens Martens-Lobenhoffer, Ines Reiche, Uwe Tröger, Klaus Mönkemüller, Peter Malfertheiner, Stefanie M. Bode-Böger

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 348 KB

english, 2007

22

Corrigendum to “Enantioselective quantification of omeprazole and its main metabolites in human serum by chiral HPLC-atmospheric pressure photoionization tandem mass spectrometry” [J. Chromatogr. B 857 (2007) 301–307]

Jens Martens-Lobenhoffer, Ines Reiche, Uwe Tröger, Klaus Mönkemüller, Peter Malfertheiner, Stefanie M. Bode-Böger

Journal:

Journal of Chromatography B

Year:

2007

Language:

english

File:

PDF, 60 KB

english, 2007

23

Passive and active systems in harmony

Klaus Bode, Matthew Winter

Journal:

Renewable Energy Focus

Year:

2007

Language:

english

File:

PDF, 844 KB

english, 2007

24

A novel brain receptor is expressed in a distinct population of olfactory sensory neurons

Sidonie Conzelmann, Olga Levai, Barbara Bode, Ulrich Eisel, Klaus Raming, Heinz Breer, Jörg Strotmann

Journal:

European Journal of Neuroscience

Year:

2000

Language:

english

File:

PDF, 1.59 MB

english, 2000

25

Interlocking transcriptomics, proteomics and toponomics technologies for brain tissue analysis in murine hippocampus

Marcus Bode, Martin Irmler, Manuela Friedenberger, Caroline May, Klaus Jung, Christian Stephan, Helmut E. Meyer, Christiane Lach, Reyk Hillert, Andreas Krusche, Johannes Beckers, Katrin Marcus, Walter

Journal:

Year:

2008

Language:

english

File:

PDF, 385 KB

english, 2008

26

Teratogenic effects of nitroimidazopyridazine on the CNS in fetal Wistar (WU) rats

Thomas Woehrmann, Jutta Volland, Klaus Tuch, Gerd Bode, Ulrich Hübel

Journal:

Archives of Toxicology

Year:

2006

Language:

english

File:

PDF, 519 KB

english, 2006

27

PET-positive fibrous dysplasia - a potentially misleading incidental finding in a patient with intimal sarcoma of the pulmonary artery

Klaus Strobel, Beata Bode, Didier Lardinois, Ulrich Exner

Journal:

Skeletal Radiology

Year:

2007

Language:

english

File:

PDF, 222 KB

english, 2007

28

Tracing Roman lead sources using lead isotope analyses in conjunction with archaeological and epigraphic evidence—a case study from Augustan/Tiberian Germania

Michael Bode, Andreas Hauptmann, Klaus Mezger

Journal:

Archaeological and Anthropological Sciences

Year:

2009

Language:

english

File:

PDF, 567 KB

english, 2009

29

Nitrocellulose dot-ELISA for serodiagnosis of schistosomiasis

Klaus Janitschke, Astrid Reinhold, Liv Bode

Journal:

Transactions of the Royal Society of Tropical Medicine and Hygiene

Year:

1987

Language:

english

File:

PDF, 665 KB

english, 1987

30

Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment

Konrad A. Bode, Kate Schroder, David A. Hume, Timothy Ravasi, Klaus Heeg, Matthew J. Sweet, Alexander H. Dalpke

Journal:

Year:

2007

Language:

english

File:

PDF, 394 KB

english, 2007

31

Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity

Mirjam Peter, Konrad Bode, Grayson B. Lipford, Florian Eberle, Klaus Heeg, Alexander H. Dalpke

Journal:

Year:

2008

Language:

english

File:

PDF, 353 KB

english, 2008

32

Carvedilol

Erika von Möllendorff, Gisbert Sponer, Klaus Strein, Wolfgang Bartsch, Bernd Müller-Beckmann, Günter Neugebauer, Harald Czerwek, Gerd Bode, Erhard Schnurr

Journal:

Cardiovascular Therapeutics

Year:

1987

Language:

english

File:

PDF, 960 KB

english, 1987

33

Endoproteinase-protein inhibitor interactions

WOLFRAM BODE, CARLOS FERNANDEZ-CATALAN, HIDEAKI NAGASE, KLAUS MASKOS

Journal:

Year:

1999

Language:

english

File:

PDF, 1.95 MB

english, 1999

34

Insights into MMP-TIMP Interactions

WOLFRAM BODE, CARLOS FERNANDEZ-CATALAN, FRANK GRAMS, FRANZ-XAVER GOMIS-RÜTH, HIDEAKI NAGASE, HARALD TSCHESCHE, KLAUS MASKOS

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.47 MB

english, 1999

35

Engineering of Selective TIMPs

HIDEAKI NAGASE, QI MENG, VLADIMIR MALINOVSKII, WEN HUANG, LINDA CHUNG, WOLFRAM BODE, KLAUS MASKOS, KEITH BREW

Journal:

Annals of the New York Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 627 KB

english, 1999

36

10.1038/380005b0

Bode, Wolfram, Gomis-R¨th, Franz-Xaver, Maskos, Klaus, Betz, Michael, Bergner, Andreas, Huber, Robert, Suzuki, Ko, Yoshida, Naoki, Nagase, Hideaki, Brew, Keith, Bourenkov, Gleb P., Bartunik, Hans

Journal:

Year:

1996

File:

PDF, 554 KB

1996

37

10.1038/37995

Bode, Wolfram, Gomis-R¨th, Franz-Xaver, Maskos, Klaus, Betz, Michael, Bergner, Andreas, Huber, Robert, Suzuki, Ko, Yoshida, Naoki, Nagase, Hideaki, Brew, Keith, Bourenkov, Gleb P., Bartunik, Hans

Journal:

Year:

1997

Language:

english

File:

PDF, 1.30 MB

english, 1997

38

10.1038/380008b0

Bode, Wolfram, Gomis-R¨th, Franz-Xaver, Maskos, Klaus, Betz, Michael, Bergner, Andreas, Huber, Robert, Suzuki, Ko, Yoshida, Naoki, Nagase, Hideaki, Brew, Keith, Bourenkov, Gleb P., Bartunik, Hans

Journal:

Year:

1996

File:

PDF, 449 KB

1996

39

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Friedrich, Rainer, Panizzi, Peter, Fuentes-Prior, Pablo, Richter, Klaus, Verhamme, Ingrid, Anderson, Patricia J., Kawabata, Shun-Ichiro, Huber, Robert, Bode, Wolfram, Bock, Paul E.

Journal:

Year:

2003

Language:

english

File:

PDF, 856 KB

english, 2003

40

Structural basis of matrix metalloproteinases and tissue inhibitors of metalloproteinases

Klaus Maskos, Wolfram Bode

Journal:

Molecular Biotechnology

Year:

2003

Language:

english

File:

PDF, 948 KB

english, 2003

41

Untersuchungen über substituierte Dithiocarbamidate

Helmut Bode, Klaus -Joachim Tusche, Hermann -Franz Wahrhausen

Journal:

Analytical and Bioanalytical Chemistry

Year:

1962

Language:

german

File:

PDF, 838 KB

german, 1962

42

Zur photometrischen Bestimmung kleiner Selenmengen

Helmut Bode, Klaus Schulze

Journal:

Analytical and Bioanalytical Chemistry

Year:

1987

Language:

german

File:

PDF, 351 KB

german, 1987

43

Zur photometrischen Arsenbestimmung mit Silber-Diäthyldithiocarbamidat

Helmut Bode, Klaus Hachmann

Journal:

Analytical and Bioanalytical Chemistry

Year:

1967

Language:

german

File:

PDF, 365 KB

german, 1967

44

über die Reaktion zwischen Arsenwasserstoff und SilberdiÄthyldithiocarbamidat

Helmut Bode, Klaus Hachmann

Journal:

Analytical and Bioanalytical Chemistry

Year:

1968

File:

PDF, 799 KB

1968

45

Untersuchungen über disubstituierte Dithiocarbaminate

Helmut Bode, Klaus-Joachim Tusche

Journal:

Analytical and Bioanalytical Chemistry

Year:

1957

Language:

german

File:

PDF, 912 KB

german, 1957

46

Current and planned disposal of sewage sludge and other waste products from the Ruhrverband wastewater treatment

Harro Bode, Klaus R. Imhoff

Journal:

Water Science and Technology

Year:

1996

Language:

english

File:

PDF, 854 KB

english, 1996

47

Dihydrofolate Reductase Deficiency Due to a Homozygous DHFR Mutation Causes Megaloblastic Anemia and Cerebral Folate Deficiency Leading to Severe Neurologic Disease

Holger Cario, Desirée E.C. Smith, Henk Blom, Nenad Blau, Harald Bode, Karlheinz Holzmann, Ulrich Pannicke, Karl-Peter Hopfner, Eva-Maria Rump, Zuleya Ayric, Elisabeth Kohne, Klaus-Michael Debatin, Yvo

Journal:

The American Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 382 KB

english, 2011

48

1.2 Å Crystal Structure of the Serine Carboxyl Proteinase Pro-Kumamolisin: Structure of an Intact Pro-Subtilase

Mireia Comellas-Bigler, Klaus Maskos, Robert Huber, Hiroshi Oyama, Kohei Oda, Wolfram Bode

Journal:

Year:

2004

Language:

english

File:

PDF, 554 KB

english, 2004

49

The 1.4 Å Crystal Structure of Kumamolysin: A Thermostable Serine-Carboxyl-Type Proteinase

Mireia Comellas-Bigler, Pablo Fuentes-Prior, Klaus Maskos, Robert Huber, Hiroshi Oyama, Kenichi Uchida, Ben M. Dunn, Kohei Oda, Wolfram Bode

Journal:

Year:

2002

Language:

english

File:

PDF, 639 KB

english, 2002

50

Crystal Structure of the Dinuclear Zinc Aminopeptidase PepV from Lactobacillus delbrueckii Unravels Its Preference for Dipeptides

Daniela Jozic, Gleb Bourenkow, Hans Bartunik, Henning Scholze, Vincent Dive, Bernhard Henrich, Robert Huber, Wolfram Bode, Klaus Maskos

Journal:

Year:

2002

Language:

english

File:

PDF, 590 KB

english, 2002

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